Strip club owner Larry Flynt and his wife, Althea, create a pornographic magazine that ignores society's morals and taboos. "Hustler" magazine brings the Flynts not only millions in profit but also the wrath of "decent" people. Flynt and his overburdened attorney find themselves in courtrooms all over the nation defending Larry against criminal and civil charges. In the meantime, Flynt is beset by paralysis, the result of an assassination attempt, drug addiction, mental illness, and Althea's failing health.
Pumpkin and Honey Bunny are two thieves who, while dining at a coffee shop, decide that the best thing to do is to rob it. Vincent and Jules, two hit men working for mob kingpin Marcellus Wallace, are sent to retrieve a very special and very mysterious briefcase for their boss. Vincent later must also show Mrs. Wallace a good time while her husband is out. Butch Coolidge is an aging prizefighter who is being paid to "take a dive", but instead, accidentally kills him opponent, and tries to flee town, but not before getting his dead father's lucky golden watch. These four seemingly unrelated stories are interwoven together in a non-linear fashion.
At midnight on New Years Eve the S.S. Poseidon is struck by a 90' tidal wave and is capsized. The Reverend Frank Scott leads nine Survivors; an elderly couple, Manny and Belle Rosen headed to Israel to see their grandson; A New York detective and his ex-prostitute wife, Mike and Linda Rogo on their second honeymoon to Italy; A young brother and sister, Robin and Susan Shelby going to meet their parents in Greece; A haberdasher James Martin; a pop singer Nonnie Parry, and a waiter from the ship Acres. They travel from the grand ballroom struggling through, steam, fire and rising water in the up-side-down ship to reach the bottom (the propeller shaft), now the top.
Several years after the deaths of Dick Buek and her father, Jill Kinmont and her mother leave Los Angeles to spend their summer in their hometown of Bishop, California. They rent a summer house from a handsome truck driver named John Boothe. Jill is instantly captivated by John, but denies it to everyone, including herself. Eventually, Jill and John fall in love, but deep fears and hurts from the past threaten to be the couple's undoing.
When 17th century explorer John Smith and a few men go up the river to trade with the Indians, he befriends the princess Pocahontas and they fall in love. While in love, Smith must obtain his duties as president of Jamestown fort and challenges to himself what is the better path for himself to take: stay with the fallen apart colony or go up the river and love Pocahontas in the wild. The Indians realize that the English do not mean to leave, so they attack. A few men at the fort decide to capture Pocahontas as a hostage so the Indians will not attack them. Smith is ordered to leave Jamestown by the King, and John Rolfe, a wealthy tobacco planter arrives at the fort. Pocahontas, now living there adapts to the English cultures and falls in love with Rolfe. She falls apart deciding who she is dedicated to, Smith or Rolfe.